DNASTAR's Lasergene Genomics Suite software provides tools to simplify your SNP discovery and analysis of multiplexed data generated by all major next-gen sequencing platforms including Roche 454, Illumina, Ion Torrent, and Pacific Biosciences. Features of the software enable you to:
- Quickly and easily assemble large data sets from all major next-gen technologies on a desktop computer—check out our benchmarks below
- Analyze SNPs using live, interactive views and comprehensive filtering tools
- SNP and small indels compared to dbNSFP, dbSNP, COSMIC, and GERP databases during assembly for all major model organisms
- Perform large-scale comparisons of SNPs across individuals and groups of indivduals, and determine the level of disruption to each gene caused by the SNPs present
For more information on using Lasergene Genomics Suite for your large-scale, multi-sample SNP projects, please see the following two videos, which demonstrate an assembly of the exomes of three individuals, and the subsequent analysis and comparision of SNPs across the group.
Lasergene Genomics Suite Reference-Guided Genome Alignment Benchmarks
|Human Genome*||Illumina||Hg19+dbSNP||3,101||3,523||112,738||32||36X||23 Hrs.|
|8 Human Exomes* (multiplex)||Illumina||Hg19+dbSNP||27||1,268||12,047||76||446X||14 Hrs.|
|Human Exome*||Illumina||Hg19+dbSNP||27||163||12,390||76||459X||2 Hrs.|
|Ion AmpliSeq™ Cancer Panel (3 multiplexed data sets)Data provided by Ion Torrent.||Ion Torrent||Hg19+dbSNP||3,101||3||99||85||500X||24 Min.|
|Fluidigm® Access Array System (2 multiplexed data sets)Data provided by Pacific Biosciences.||Pac Bio||Fluidigm human amplicons||0.1||< 1||7||180||500X||1 Min.|
*Data sets for these projects were obtained from NCBI's Short Read Archive.
** Assembly times were calculated using a computer with a 4 Disk RAID-0.