Cancer Genomics
DNASTAR's Lasergene Genomics Suite includes software for cancer genomics, enabling you to identify mutations and genes that contribute to the development of a cancer cell. Features of the Lasergene Genomics Suite software include:
Quick assembly of large data sets from all major next-gen technologies on a desktop computer - check out our benchmarks below.
Detection and analysis of SNPs using live, interactive views and comprehensive filtering tools
Direct connection to the dbSNP, COSMIC and GERP databases
The ability to perform large-scale comparisons of SNPs across individuals and groups of indivduals, and determine the level of disruption to each gene caused by the SNPs present
| For more information on using Lasergene Genomics Suite in your cancer genomics research, please see the following video, which briefly demonstrates an assembly of the exomes of four individuals, and the subsequent analysis and comparision of SNPs across the group. |
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Lasergene Genomics Suite Benchmarks for Human Reference-Guided Assemblies
|
Data Set |
Sequence Technology |
Reference Sequence |
Genome Size (Mbp) |
Number of Reads (M) |
Number of Bases (Mbp) |
Read Length (bp) |
Coverage |
Assembly Time** |
| Human Genome* |
Illumina |
Hg19+dbSNP |
3,101 |
3,523 |
112,738 |
32 |
36X |
23 Hrs. |
| 8 Human Exomes* (multiplex) |
Illumina |
Hg19+dbSNP |
27 |
1,268 |
12,047 |
76 |
446X |
14 Hrs |
| Human Exome* |
Illumina |
|
27 |
163 |
12,390 |
76 |
459X |
2 Hrs. |
Ion AmpliSeq™ Cancer Panel (3 multiplexed data
sets) |
Ion Torrent |
|
3,101 |
3 |
99 |
85 |
500X |
24 Min. |
Fluidigm® Access Array System (2 multiplexed data
sets) |
Pacific Biosciences |
Fluidigm human amplicons |
0.1 |
< 1 |
7 |
180 |
500X |
1 Min. |
*Data sets for these projects were obtained from NCBI's Short Read Archive.
**Assembly times were calculated using a computer with a 4-Disk RAID-0.
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