Lasergene Product Notifications

General Lasergene

DNASTAR no longer supports Protean

Date: 10/11/17

 

Version Affected: 15.0 and later

 

Version Fixed: N/A

 

Issue: As of October 11, 2017, corresponding with the release of Lasergene 15.0, DNASTAR’s Protean application is being retired. We will continue to support Protean’s successor, Protean 3D, which contains the key functionality of the retired application.

 

Resolution: For assistance in upgrading to the latest version of Lasergene, including the Protean 3D application, please contact DNASTAR at 866-511-5090 or sales@dnastar.com.

Attempt to check out commuter license on Mac leads to “Check Out Error” message

Date: 9/16/17

 

Version Affected: All

 

Version Fixed: N/A

 

Issue: For DNASTAR License Server configurations authorized after September 15, 2017, the commuter license manager on Macintosh may give the following message:

 

Check Out Error

Unable to check out

Error [125]: Required locking criteria for local request is not available on your machine.

.

Resolution: We are working to fix this issue. If you are experiencing an issue attempting to check out a commuter license on Macintosh, please contact DNASTAR at 866-511-5090 or sales@dnastar.com.

DNASTAR no longer supports Lasergene 11

Date: 3/2/17

 

Version Affected: Lasergene 11 (and earlier)

 

Version Fixed: N/A

 

Issue: As of March 2, 2017, corresponding with the release of Lasergene 14.1, DNASTAR no longer supports Lasergene 11 (or earlier).

 

Resolution: Please contact DNASTAR at 866-511-5090 or sales@dnastar.com for assistance in upgrading to the latest version of Lasergene.

Issues running Lasergene on Macintosh 10.12 (Sierra)

Date: 3/2/2017

 

Version Affected: 14.0 and earlier

 

Version Fixed: 14.1

 

Issue: Users of Lasergene 14.0 and earlier have experienced a variety of issues when running Lasergene applications on Macintosh 10.12 (Sierra). Several issues pertain to all Sierra machines, while others occur only on Sierra machines using the Retina high-definition display. Examples of known issues include:

 

  • Lasergene application help does not display.
  • Except in SeqBuilder, initiating a BLAST search causes the Lasergene application to close.
  • On Retina displays only, dialogs for adding, opening, saving or exporting files do not display correctly, or  cause the Lasergene application to close.

 

Resolution: These issues have been resolved with the release of Lasergene 14.1. To regain full software functionality, log in to your DNASTAR account and update to the latest version of Lasergene. If you have questions or need assistance updating your software, please contact DNASTAR at 866-511-5090 or sales@dnastar.com.

 

For best results, we also recommend updating your Macintosh machine to Sierra 10.12.4 when that version is released.

Issues related to NCBI’s transition from “http” to “https” URLs

Date: 9/29/2016

 

Version Affected: Version 13 and previous

 

Version Fixed: 14.0

 

Issue: By December 31, 2016, all U.S. federal government entities will be required to use secure “https” websites instead of general “http” websites. The National Center for Biotechnology Information (NCBI) has announced they plan to make this change on September 30, 2016. We anticipate that NCBI will disable some “http” functionality periodically through the end of 2016, and will disable most or all of it after the end of 2016.

 

NCBI’s changes will cause the following functions to be disabled in all versions of Lasergene through version 13:

 

  • BLAST searching and downloads (multiple applications)
  • Entrez searching and downloads (multiple applications)
  • Genome downloads from NCBI (ArrayStar)

 

The following Lasergene functions will work only as long as NCBI supports automatic redirects:

 

  • dbSNP links (SeqMan Pro and ArrayStar)
  • Protein Database (PDB) links (Protean 3D)

 

Resolution: This was fixed in Lasergene 14.0, which now directs communications to the new “https” URLs. To resolve the issue, log in to your DNASTAR account to update to the latest version of Lasergene. Please contact DNASTAR at 866-511-5090 or sales@dnastar.com if you need assistance.

Issues related to NCBI’s transition from GI Numbers to Accession Numbers

Date: 9/29/2016

 

Version Affected: 13 and previous

 

Version Fixed: 14.0

 

Issue: The National Center for Biotechnology Information (NCBI) has announced that they are changing certain file formats and restructuring their EUtils databases. The date of this change has not been announced, but will likely occur in Fall 2016.

 

Many Lasergene applications allow you to search and download files from NCBI databases. The upcoming NCBI changes will affect BLAST/Entrez searching and Transcript Annotation Database functionality  in all existing versions of Lasergene (through version 13). For example, Lasergene currently utilizes NCBI’s present identification system of “Genome Identifier Number” (GI #) as the unique sequence identifier,  though “Accession Numbers” are also supported in many situations. As one of the changes, NCBI intends to begin using “Accession Numbers” as the unique sequence identifier.

 

Resolution: With the launch of Lasergene 14.0, all applicable Lasergene applications now support “Accession Numbers” as the unique sequence identifier. To resolve the issue, log in to your DNASTAR account to update to the latest version of Lasergene. Please contact DNASTAR at 866-511-5090 or sales@dnastar.com if you need assistance.

DNASTAR no longer supports Lasergene 10, ArrayStar 5 or SeqMan NGen 4

Date: 3/1/16

 

Version Affected: Lasergene 10, ArrayStar 5, and SeqMan NGen 4 (and earlier)

 

Version Fixed: N/A

 

Issue: As of March 1, 2016, corresponding with the release of Lasergene 13.0, DNASTAR no longer supports Lasergene 10, ArrayStar 5 or SeqMan NGen 4 (or earlier).

 

Resolution: Please contact DNASTAR at 866-511-5090 or sales@dnastar.com for assistance in upgrading to the latest version of Lasergene.

BLAST searching fails for Lasergene versions 12.3 and earlier

Date: 3/1/16

 

Version Affected: 12.3 and earlier

 

Version Fixed: N/A

 

Issue: Sometime in 2016, NCBI will be changing its BLAST database file structure and will no longer provide the original XML format used by Lasergene version 12.3 and earlier. After NCBI implements this change, those Lasergene versions will be unable to perform a BLAST search and will instead return a non-specific error message such as: “BLAST failed to return results.” In addition (or as an alternative) to this message, a file named blast-error.txt may appear on the desktop.

 

Note that this issue will not affect Entrez database text searches, only BLAST search queries.

 

Resolution: In order to continue using Lasergene’s BLAST searching functionality, you will need to upgrade to the current version of Lasergene (13.0 or higher). Please contact DNASTAR at 866-511-5090 or sales@dnastar.com for assistance.

Macintosh OS X 10.11 “El Capitan” is not compatible with Lasergene version 12.3.1 or earlier

Date: 10/13/15

 

Version Affected: 12.3.1 and earlier

 

Version Fixed: 12.3.2

 

Issue:  Macintosh released operating system OS X 10.11 “El Capitan” on 9/30/15. This operating system is incompatible with Lasergene version 12.3.1 or earlier. If you have Lasergene version 12.3.1 or earlier, updating to El Capitan will cause the loss of important Lasergene functionality, including the ability to:

 

  • Open, close and save files.
  • Run applications through the command-line (SeqMan NGen, SeqNinja).

 

Resolution: This issue is fixed in Lasergene 12.3.2, released on 10/13/15. If you download and install this version of Lasergene (or later), you may update your Macintosh system to “El Capitan” while retaining full Lasergene functionality.

 

Please contact DNASTAR at 866-511-5090 or sales@dnastar.com for information on upgrading your applications to the latest versions.

 

 

DNASTAR no longer supports Windows XP

Date:  7/29/15

 

Version Affected:  12.3.1 and higher

 

Version Fixed:  N/A

 

Issue:  As of July 29, 2015, corresponding with the release of Lasergene 12.3.1, DNASTAR no longer supports running our software on Windows XP systems.

 

Resolution: Please contact DNASTAR at 866-511-5090 or sales@dnastar.com for assistance.

 

Unsecured network systems risk license server vulnerability

Date: 6/16/2015

 

Version Affected: DNASTAR Lasergene License Server 11.0 to 12.2

 

Version Fixed: DNASTAR Lasergene License Server 12.3

 

Issue:  A vulnerability has been discovered in the third-party license server executable (“lserv”) installed with the network version of Lasergene. If an outside party attempts to exploit this vulnerability, the user may receive unexpected error messages from lserv. This issue has only been reported for networks that do not follow recommended levels of network security.

 

Resolution:  This vulnerability was addressed with the release of DNASTAR Lasergene License Server 12.3 on July 1, 2015. To correct the issue, download and install the latest DNASTAR Lasergene License Server for Windows or Macintosh, as described in the DNASTAR Lasergene Network Setup Guide. If you need assistance, please contact DNASTAR at 866-511-5090 or support@dnastar.com.

 

After installing Lasergene on Windows, antivirus programs may report “Shellshock” vulnerability

Date: 10/8/2014

 

Version Affected: 12.0 and higher

 

Version Fixed: N/A

 

Issue: To support MegAlign’s MAFFT alignment algorithm, the Windows version of Lasergene installs and uses a version of GNU Bash containing the recently published ShellShock vulnerability. Antivirus programs may flag this as a risk.

 

The GNU Bash installed by Lasergene is not exposed to external attackers, as it is installed for use only by MegAlign Pro. It is not used by web servers or other known attack vectors. Therefore, we believe that Lasergene installation poses no risk to our customers.

 

ShellShock vulnerability is described further on the U.S. CERT website.

 

Note: This issue does not affect Macintosh installations of Lasergene.

 

Resolution: We are actively working toward updating GNU Bash in a future release of Lasergene.

 

If desired, you may remove this version of GNU Bash from the MegAlign Pro installation. Doing so will make the MAFFT alignment engine unavailable until you perform a new Lasergene installation. For assistance in removing GNU Bash, contact DNASTAR at 866-511-5090 or support@dnastar.com.

 

A warning message that the “identity of the developer cannot be confirmed” appears when attempting installation of DNASTAR software on Macintosh OS X 10.9.5 and later

Date: 9/18/2014

 

Version Affected: 12.0 and 12.0.1

 

Version Fixed: 12.1

 

Issue: Macintosh OS X 10.9 (Mavericks) and later require a “v2” signature. Lasergene 12.0 and 12.0.1 have a “v1” signature. Therefore, when attempting to install Lasergene 12.0 or 12.0.1 or its components on Macintosh OS X 10.9.5 (or later), the following message appears: “[ApplicationName] 12.x.x Mac Install can’t be opened because the identity of the developer cannot be confirmed.”

 

Resolution:

 

To correct this issue:

 

After the release of Lasergene 12.1, please log in and download the most recent version of the software. If you need assistance, contact DNASTAR at 866-511-5090 or support@dnastar.com for help.

 

Prior to the release of Lasergene 12.1, or if you do not wish to upgrade to that version, you may circumvent the issue as follows:

 

  1. Click the OK button to close the warning.
  2. Ctrl+click on the file named [ApplicationName] 12.x.x Mac Install and select Open. You will see a warning that appears similar to the original warning.
  3. Click the Open button at the bottom of the new message.

 

The installer will now run as normal.

 

2 comments

  1. Question: Is Lasergene Access Points version 11 (Lasergene Clients) compatible with Apple 10.10 Yosemite. We have 3 license. 2 Lasergene Client license ver. 11 are currently running on Apple OS 10.6. We like to have the 3rd run on the Apple 10.10 Yosemite system.

    Thanks,

    Pete

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>

Current ye@r *