» Printable PDF of Version Comparison
| Lasergene Version Comparison |
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| 5.0* | 6.0** | 7.0 | 8.0 | |
| SeqMan Pro - Sequencing Project Manager |  |
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| SNP filtering in reports | |
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| Codon display in SNP reports | |
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| Direct annotation capability | |
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| Faster assembly of large sequence projects | |
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| Add new Features by selecting the region or BLASTing | |
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| Full Feature support on sequences and consensus | |
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| Analyze NextGen sequence data assembled with SeqMan NGen for Roche 454 and Illumina platforms | |
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| Primer Walking system to handle larger numbers of sequences | |
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| Assemble E. coli size genomes and large EST and SNP data sets | |
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| Flowspace diagram for 454® assembly visualization | |
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| Read 454® output files (.sff, .fna, .fas, and .qual types) | |
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| Maximum Expected Coverage repeat region analysis | |
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| Enhanced vector trimming | |
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| SNP Discovery | |
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| Advanced scripting ability | |
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| Ability to import and edit Sequencher™ assemblies | |
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| Pro Assembler handles large assemblies of traditional and pyrosequencing data quickly | |
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| Import and edit Phrap assemblies | |
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| View multiple consensus sequences simultaneously | |
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| Utilize dual-end sequence data | |
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| Auto save assembly projects | |
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| Explicit view of vector trim coordinates | |
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| Ignore short fragments in assemblies | |
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| Locate regions of alignments for contig splitting | |
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| Automatically remove poor quality fragments and vector data | |
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| SeqBuilder - Sequence editor, feature annotator, cloning | |
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| Design Primers around selected features | |
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| Enhanced export to GenVision | |
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| Short cut compatible enzyme selector | |
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| Import Vector NTI primers | |
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| Detached feature labels | |
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| Copy as picture, export to Adobe® Illustrator® | |
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| Ability to batch import Vector NTI® files retaining feature names | |
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| Automated virtual cloning — site-directed, TA, TOPO® and Gateway® protocols | |
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| Create graphically-rich, publication-quality linear and circular maps | |
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| Display and edit in multiple views simultaneously | |
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| Cut/paste sequences and annotations into many views | |
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| View ORFs, annotations, translations and restriction cut sites | |
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| MegAlign - Multiple sequence alignments | |
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| Bootstrapping | |
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| ClustalW multiple alignment method | |
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| Export the majority consensus of alignments | |
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| Copy sections of the alignment report to the clipboard | |
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| Create sub-alignments from multiple sequence alignments | |
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| Export to .paup, .pau and .nex | |
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| Select a subsection of an alignment and clone to new alignment project | |
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| Select a subsection of an alignment report for copying and pasting image to clipboard | |
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| Output alignments as plain text | |
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| Export data for further analysis or publication | |
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| Export sequences as FASTA | |
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| PrimerSelect - Oligo Primer Design | |
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| Automatic search for best primer pairs | |
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| Reports for primer composition, predicted hairpin structures and self dimers | |
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| Create unique primer catalog | |
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| GeneQuest - Gene Finding | |
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| Updated Transcription Factor binding sites | |
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| Enhanced export to GenVision for visualizations | |
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| Enhanced sorting, Feature display and editing | |
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| Automatic coding region prediction | |
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| GC content plot | |
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| Identify region where translation matches specified protein sequence file | |
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| Identify and annotate coding regions | |
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| Protean - protein structure analysis | |
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| Enhanced export to GenVision for visualizations | |
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| Implement protein profile pattern searches | |
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| Updated Prosite database | |
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| Ability to sort features by type, name and position | |
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| Secondary structural analysis | |
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| Automatic prediction of proteolytic cleavage sites | |
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| Locate potential antigenic determinants and sites from primary sequence data | |
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| BLAST and Entrez | |
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| BLAST and Entrez searching in all modules | |
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| Directly enter sequences from NCBI-BLAST or Entrez | |
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| Supports multiple servers | |
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| BLAST/Entrez results may be copied, printed and saved as text | |
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| Direct download in module | |
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| Print and save result | |
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| Text searching | |
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| DataManager | |
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| Workflow integration | |
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| Create sequence datasets - catalog vectors and oligos | |
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| Shared memory communication protocol (shmRPC) | |
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| Project management | |
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| Synchronize sequences in shared modules | |
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| Share feature creation between modules | |
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| Network License | |
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| Sassafras Keyserver compatibility | |
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| DNASTAR network | |
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| Dual Platform Support — Macintosh & Windows | |
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| Windows Vista™ compatible | |
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| Native on Macintosh Intel computers | |
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* DNASTAR no longer supports Lasergene version 5.
** DNASTAR will no longer support Lasergene version 6 past December 31, 2008.