DNASTAR Next-Gen Sequencing Software Solutions
SeqMan NGen is a High Accuracy NGS Assembler:  Assessment with NA12878 Reference Materials


Large-Scale, Multi-Sample SNP Analysis

DNASTAR's Lasergene Genomics Suite software provides tools to simplify your SNP discovery and analysis of multiplexed data generated by all major next-gen sequencing platforms including Roche 454, Illumina, Ion Torrent, Pacific Biosciences, and SOLiD. Features of the software enable you to:

  • Quickly and easily assemble large data sets from all major next-gen technologies on a desktop computer - check out our benchmarks below
  • Analyze SNPs using live, interactive views and comprehensive filtering tools
  • Directly connect to the dbSNP/COSMIC/GERP databases for most model organisms
  • Perform large-scale comparisons of SNPs across individuals and groups of indivduals, and determine the level of disruption to each gene caused by the SNPs present
  • For more information on using Lasergene Genomics Suite for your large-scale, multi-sample SNP projects, please see the following two videos, which demonstrate an assembly of the exomes of three individuals, and the subsequent analysis and comparision of SNPs across the group.

    PDF Icon Rapid Assembly and Analysis of Clinical Sequencing Data on a Desktop Computer: Using DNASTAR Software to Identify Potential Disease-Causing Mutations


    Request a fully-functional, free trial of Lasergene Genomics Suite.



    Lasergene Genomics Suite Benchmarks for Human Reference-Guided Assemblies

    Data Set
    Sequence Technology
    Reference Sequence
    Genome Size (Mbp)
    Number of Reads (M)
    Number of Bases (Mbp)
    Read Length (bp) Coverage

    Assembly Time**

    Human Genome* Illumina Hg19+dbSNP 3,101 3,523 112,738 32 36X 23 Hrs.
    8 Human Exomes* (multiplex) Illumina


    27 1,268 12,047 76 446X 14 Hrs
    Human Exome*
    2 Hrs.
    Ion AmpliSeq™ Cancer Panel (3 multiplexed data
    sets) Data provided by Ion Torrent.
    Ion Torrent
    85 500X
    24 Min.
    Fluidigm® Access Array System (2 multiplexed data
    sets) Data provided by Pacific Biosciences.
    Pacific Biosciences Fluidigm human amplicons 0.1 < 1 7 180 500X 1 Min.


    *Data sets for these projects were obtained from NCBI's Short Read Archive.

    **Assembly times were calculated using a computer with a 4-Disk RAID-0.