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Lasergene 19.0 Release Notes

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      • Automated Virtual Cloning
      • Clone Sequence Verification
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      • Gel Electrophoresis Simulation
      • Gene Homology Alignment
      • Multiple Sequence Alignment
      • Pairwise Sequence Alignment
      • PCR Site-Directed Mutagenesis
      • PCR Primer Design
      • Phylogenetic Analysis
      • Plasmid Maps
      • Sanger Sequence Assembly
      • Sequence Editing and Annotation
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      • Protein Stability Prediction
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      • Protein Structure Analysis
      • Protein Structure Prediction
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      • Clinical Research
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      • Mauve Genome Alignment
      • Metagenomic Assembly
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      • Viral Genome Analysis
      • Whole Exome/Genome Sequencing
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      • ChIP-Seq Data Analysis
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LASERGENE GENOMICS

Next-gen sequencing software for thorough data analysis.

Lasergene Genomics provides everything you need for next-gen sequencing including assembly, alignment, and analysis.  Simplified next gen software, integrated into a single package.  The suite supports all major traditional and next-generation sequencing technologies, including Illumina and Ion Torrent, making it easy to work with your data for any type of project.  Find out why our software is #1 in accuracy for variant detection and SNP analysis.

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Supported Workflows

ChIP-Seq Data Analysis

Clinical Research

De Novo Genome Assembly

De Novo Transcriptome Assembly

Mauve Genome Alignment

Metagenomic Assembly

RNA-Seq Alignment

Variant Analysis

Whole Exome/Genome Sequencing

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Lasergene Genomics Gene Resequencing Results

Analysis Software for All Major Next-Gen Sequencing Technologies

Illumina+sequencing
Ion Torrent Sequencing
PacBio Sequencing

Included Applications and Features

SeqMan NGen Icon: Accurate Alignment and Assembly of GenomicSequencing Data

SeqMan NGen

Accurate Alignment and Assembly of Genomic Sequencing Data

  • Assemble genome and transcriptome data from all major NGS and Sanger sequencing platforms.
  • Align RNA-Seq, ChIP-Seq, miRNA, exome and whole genome sequencing data.
  • Run assemblies locally or use DNASTAR Cloud Assemblies to utilize our cloud computing resources.
  • Open results in SeqMan Ultra, ArrayStar, or GenVision Pro for comprehensive downstream analysis after assembly.

SeqMan Ultra Icon

SeqMan Ultra

Sequence Assembly Analysis and Editing

  • Visualize the orientation and distance between contigs.
  • Identify large insertions and deletions and evaluate coverage.
  • Order contigs into genomic scaffolds.
  • Add sequences to close gaps between contigs.
  • Analyze variants within the context of the alignment.

SeqMan Pro, DNASTAR’s legacy application for sequence assembly analysis, is also included in Lasergene 17, but will eventually be completely replaced by SeqMan Ultra.

Array Star Icon: Gene Expression and SNP Analysis

ArrayStar

Gene Expression and SNP Analysis

  • Evaluate global gene expression experiments, compare sequence variation, analyze RNA-Seq, ChIP-Seq, CNV, miRNA, and more.
  • Analyze variants using assembly projects and/or SNP data from VCF files.
  • Utilize annotation data from dbSNP and other SNP and gene databases to enrich and filter variant data.
  • Import oligonucleotide microarray and spotted array data.
  • Isolate gene mutations of interest using graphically rich visualizations, and identify their biological significance.

GenVision Pro Icon: Genomic Visualization Software

GenVision Pro

Genomic Visualization Software

  • Visualize genomic sequencing results with high-quality, highly-customizable images that are easily exported for publication.
  • Browse and compare data sets for RNA-Seq, ChIP-Seq, CNV, exome and whole genome sequencing projects.
  • Compare coverage and peak plots to interpret gene expression and regulation.
  • Analyze mRNA isoforms and view coverage along exons in RNA-Seq data using Sashimi plots.

computer

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Supporting all major next-gen sequencing workflows and technologies

Genomics

• Reference guided genome and exome assemblies
• De novo genome assembly
• Targeted sequencing and gene panels
• Clinical research
• Metagenomics
• SNP detection accuracy >99%
• Copy number variation (CNV) calculation

Integrated Data Analysis and Visualization

• Visualization and analysis of genomic variation, gene expression and gene regulation data in a single project
• Genome-scale, multi-sample analysis and browsing for any project type
• Sanger sequencing validation of NGS assemblies and variant calls
• Viral-host integration analysis

Transcriptomics

• De novo transcriptome assembly with auto-mRNA annotation
• RNA-Seq gene expression analysis
• ChIP-Seq peak detection
• Microarray analysis
• miRNA discovery and quantification

Isoform Analysis for RNASeq

Lasergene Genomics PDF

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