Use NovaFold Antibody to predict highly accurate antibody models from sequence data in minutes.
Antibody modeling is an important tool for antibody design and optimization and accuracy is paramount. Many antibody modeling tools rely solely on homology modeling, but NovaFold Antibody’s unique algorithm generates models of antibodies and antibody fragments by combining homology modeling for framework regions and fragment-based or ab initio modeling for hypervariable loop regions, resulting in highly accurate antibody structure predictions. Simply provide sequences for the light chain, the heavy chain, or both, and NovaFold Antibody will return an annotated report that includes the predicted antibody models, as well as the highest likelihood heavy chain and light chain templates and annotations for locations of CDR loops. Easily view antibody modeling results with annotations in Protean 3D, part of Lasergene Protein, which allows you to fully customize the rendering to aid in visualization, or to prepare publication-quality images to export. Antibody modeling with NovaFold Antibody can also be used in conjunction with NovaDock to predict the structure and binding of antibody-antigen complexes.