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Sequence Alignment

DNASTAR's Lasergene Core Suite provides MegAlign, an application offering both DNA and protein sequence alignment using a range of pairwise and multiple alignment methods. From the alignments generated, phylogenetic trees as well as reports and tables that show the numerical data underlying the comparisons can be created. Features of the Lasergene Core Suite software enable you to:

  • Align DNA, protein, or DNA + protein sequences via pairwise and multiple sequence alignment algorithms including Clustal, Jotun Hein, Wilbur-Lipman, Martinez Needleman-Wunsch, Lipman-Pearson and Dotplot analysis. 
  • Easily create sub alignments by selecting ranges of longer alignments to create neat blocks of similarity or to remove the ‘ragged’ termini due to length variance in your data.
  • Download sequences directly from NCBI or a database using accession numbers, BLAST, or text searches to match the highlighted segment of your current sequence or to add a search result to your current project.

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    Request a fully-functional, free trial of DNASTAR Lasergene.

     

     

    For an overview of this workflow, please see the brief video below: