The Transmembrane – von Heijne track predicts hydropathy based on the interaction between the signal sequence and membrane, using the approach of von Heijne et al., 1981. The Transmembrane – von Heijne method is similar to Goldman-Engleman-Steitz, another Protean 3D method that uses the Hopp-Woods algorithm. The von Heijne method uses estimates of the standard free energy transfer of residues that transition from a random coil conformation in water to a helical conformation in a non-polar environment.
In the Tracks panel, expand Transmembrane and check the box next to von Heijne. The track will now be visible in the Analysis view
Select the track in the Tracks panel. Open the Track Options section, which appears as follows:
- Residues to Average – number of residues to be averaged when constructing each point in the plot. The default is 17.
Click if you wish to return to the default settings.
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