Date: 10/20/26

Version Affected: All

Version Fixed: NA

Issue: When running a BLAST search from within a Lasergene application, the search either times out or takes an excessive amount of time to complete. This is caused by a recent change that NCBI made on their end in an effort to prevent users from abusing the service by doing high-volume searches.

Resolution: We are looking for a solution to this issue. In the meantime, two workarounds are available:

• Use the Local BLAST functionality already present in Lasergene. To set up a local BLAST database, see this user guide topic.

• Initiate any online searches at the NCBI website rather than through a Lasergene application.

If you need assistance, please contact us at 866-511-5090 or [email protected].