Conclusion

Next-generation sequencing (NGS) of whole genomes, exomes, and RNA-Seq data is a powerful tool in biomedical research and diagnostics. However, sifting through the vast amount of NGS data to find the most relevant variants can be like looking for a polar bear in a snowstorm. Incorrect or deficient annotations can cause you to overlook potentially disease-causing variants. Open source and commercial tools have been developed to address this issue, but often, a dozen or more unrelated tools must be mastered in order to perform the analysis.

In response, DNASTAR has developed Lasergene Genomics, a fully integrated variant analysis and annotation pipeline with an intuitive, easy-to-use interface. Lasergene Genomics and its Variant Annotation Database greatly simplify variant analysis so that you can get accurate answers without needing a PhD in bioinformatics. With handy links from the GenVision Pro variants table to comprehensive online databases the once time-consuming job of variant analysis is now faster, easier, and more accurate than ever before.