LASERGENE GENOMICS
Next-gen sequencing software for thorough data analysis.
Lasergene Genomics provides everything you need for next-gen sequencing including assembly, alignment, and analysis. Simplified next gen software, integrated into a single package. The suite supports all major traditional and next-generation sequencing technologies, including Illumina and Ion Torrent, making it easy to work with your data for any type of project. Find out why our software is #1 in accuracy for variant detection and SNP analysis.
Automated Genome Closure
ChIP-Seq Data Analysis
De Novo Genome Assembly
De Novo Transcriptome Assembly
Genomic Visualization
Metagenomics
Reference-Guided Genome Alignment
RNA-Seq Alignment
SNP to Structure Analysis
SNP Validation Control
Variant Analysis
Whole Exome/Genome Sequencing
Analysis Software for All Major Next-Gen Sequencing Technologies
Included Applications and Features
SeqMan NGen
Accurate Alignment and Assembly of Genomic Sequencing Data
- Assemble genome and transcriptome data from all major NGS and Sanger sequencing platforms.
- Align RNA-Seq, ChIP-Seq, miRNA, exome and whole genome sequencing data.
- Run assemblies locally or use DNASTAR Cloud Assemblies to utilize our cloud computing resources.
- Open results in SeqMan Ultra, ArrayStar, or GenVision Pro for comprehensive downstream analysis after assembly.
SeqMan Ultra
Sequence Assembly Analysis and Editing
- Visualize the orientation and distance between contigs.
- Identify large insertions and deletions and evaluate coverage.
- Order contigs into genomic scaffolds.
- Add sequences to close gaps between contigs.
- Analyze variants within the context of the alignment.
SeqMan Pro, DNASTAR’s legacy application for sequence assembly analysis, is also included in Lasergene 17, but will eventually be completely replaced by SeqMan Ultra.
ArrayStar
Gene Expression and SNP Analysis
- Evaluate global gene expression experiments, compare sequence variation, analyze RNA-Seq, ChIP-Seq, CNV, miRNA, and more.
- Analyze variants using assembly projects and/or SNP data from VCF files.
- Utilize annotation data from dbSNP and other SNP and gene databases to enrich and filter variant data.
- Import oligonucleotide microarray and spotted array data.
- Isolate gene mutations of interest using graphically rich visualizations, and identify their biological significance.
GenVision Pro
Genomic Visualization Software
- Visualize genomic sequencing results with high-quality, highly-customizable images that are easily exported for publication.
- Browse and compare data sets for RNA-Seq, ChIP-Seq, CNV, exome and whole genome sequencing projects.
- Compare coverage and peak plots to interpret gene expression and regulation.
- Analyze mRNA isoforms and view coverage along exons in RNA-Seq data using Sashimi plots.
Supporting all major next-gen sequencing workflows and technologies
Genomics
• Reference guided genome and exome assemblies
• De novo genome assembly
• Targeted sequencing and gene panels
• Cancer genomics
• Metagenomics
• SNP detection accuracy >99%
• Copy number variation (CNV) calculation
Integrated Data Analysis and Visualization
• Visualization and analysis of genomic variation, gene expression and gene regulation data in a single project
• Genome-scale, multi-sample analysis and browsing for any project type
• Sanger sequencing validation of NGS assemblies and variant calls
• Viral-host integration analysis
Transcriptomics
• De novo transcriptome assembly with auto-mRNA annotation
• RNA-Seq gene expression analysis
• ChIP-Seq peak detection
• Microarray analysis
• miRNA discovery and quantification
