SeqMan NGen

In the ever-expanding field of genomic sequence assembly software, Lasergene Genomics stands alone, in part due to SeqMan NGen — our revolutionary assembler that enables you to set up your entire genomic sequencing project and initiate assembly in mere minutes. SeqMan NGen automates tasks that typically require extensive manual intervention, including automated organization of replicates, built-in access to diverse genome template packages, and automatic incorporation of BED and VCF files. During assembly, SeqMan NGen automatically detects, annotates, and filters variants, including access to gnomAD VCF filtering for enhanced analysis of tumor data.

SeqMan NGen’s patented algorithms enable you to assemble and align resequencing data, transcriptomic data, and de novo genomic sequencing data with unsurpassed ease and speed.

The application features workflows for short-read data from Sanger, Illumina, and IonTorrent; and long-read data from ONT and PacBio, including PacBio Iso-Seq data. In addition to our patented algorithms, you can also create assemblies utilizing the built-in GATK Mutect2 somatic variant caller or the GATK HaplotypeCaller, for high-quality germline variant discovery.

Should your project require more computing power, SeqMan NGen provides integrated access to DNASTAR Cloud Assemblies, so that you can utilize our cloud computing resources and free up your local computer to do other things.