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Lasergene 19.0.1 Release Notes

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  • Workflows
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      • Automated Virtual Cloning
      • Clone Sequence Verification
      • ELN Integration
      • Gel Electrophoresis Simulation
      • Gene Homology Alignment
      • Multiple Sequence Alignment
      • Pairwise Sequence Alignment
      • PCR Site-Directed Mutagenesis
      • PCR Primer Design
      • Phylogenetic Analysis
      • Plasmid Maps
      • Sanger Sequence Assembly
      • Sequence Editing and Annotation
    • Protein Analysis
      • Antibody Modeling
      • Antibody Phage Display
      • Epitope Prediction
      • Protein Docking
      • Protein Sequence Analysis
      • Protein Stability Prediction
      • Protein Structural Alignment
      • Protein Structure Analysis
      • Protein Structure Prediction
    • Genomics
      • Clinical Research
      • De Novo Genome Assembly
      • Mauve Genome Alignment
      • Metagenomic Assembly
      • Variant Analysis
      • Viral Genome Analysis
      • Whole Exome/Genome Sequencing
    • Transcriptomics
      • ChIP-Seq Data Analysis
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      • RNA-Seq Alignment and Analysis
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Lasergene 17.6 Release Notes

March 22, 2024 featured post, Product Release, Product Updates

LASERGENE 17.6 RELEASE NOTES

Lasergene 17.6 is now available to download.

This release includes:

  • Significant usability improvements for protein analysis in Protean 3D
  • New NovaFold AI-Multimer workflow using AlphaFold-Multimer method
  • Powerful new functionality for sequence alignments and phylogenetic analysis in MegAlign Pro
  • Updates for RNA-Seq and templated genome alignments in Lasergene Genomics
  • Bug fixes for SeqBuilder Pro and SeqMan Ultra
SEE DETAILS
scientists

Updates for sequence alignments in MegAlign Pro include:

  • A new gene homology alignment algorithm enables users to identify and compare subsets of homologous genes in bacterial genomes or eukaryotic chromosomes with ease
  • RAxML-NG is now available for fast and accurate Maximum Likelihood phylogenetic inference and bootstrapping calculations
  • Gap editing allows adding, removing, and shuffling gaps in the alignment
  • Translate nucleic sequences or subsequences into a protein alignment, with a single click
  • Use a translation track to guide sequence trimming before an alignment, or for gap editing afterward
Gene homology MAP

Improvements for protein analysis in Protean 3D include:

  • Updated rendering engine that allows Protean 3D to run natively on macOS and provides more photo-realistic images
  • New NovaFold AI-Multimer workflow for predicting the structure of multimeric assemblies using the AlphaFold-Multimer method
  • WYSIWYG (What-You-See-Is-What-You-Get) selection in the Structure view enables precise selection directly on the structure
  • Custom label creation for atoms, residues, and other structural components
  • The ability to export 3D models for use in other applications
NovaDock AI AlphaFold Multimer

Updates for NGS workflows in Lasergene Genomics include:

  • Auto-generation of PCA plots and Volcano plots for differential gene expression using EdgeR or DESeq2 for RNA-Seq alignments.
  • Updated human genome template packages for whole exome/genome sequencing and variant analysis
  • Several bug fixes in SeqMan Ultra
RNA-Seq Plots from Lasergene Genomics

Lasergene 17.6 Webinars

Unlocking RNA-Seq Data: From Reads to Results

Wednesday, July 24th, 2024 at 11:00 AM CDT

SAVE MY SEAT

Gene Homology at Scale

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The Easy Way to Predict Structures with AlphaFold-Multimer

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