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Lasergene 17.2.1 Release Notes

January 20, 2021 Product Updates

Lasergene 17.2.1 is now available to download. This patch release includes support for macOS Big Sur, new functionality in MegAlign Pro, new features in Protean 3D, and several bug fixes in SeqMan Ultra and SeqBuilder Pro.

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Global Updates

  • Compatibility with macOS Big Sur.

MegAlign Pro Enhancements and Updates

  • Added the ability to re-root phylogenetic trees in MegAlign Pro following a multiple sequence alignment to support customizations for tree publication or presentation.
  • Added new functionality for selecting individual phylogenetic tree branches as well as individual leaves for styling, giving you more control over the appearance of your tree.
  • Fixed an issue where the Feature track was excluded when exporting an image.
  • Fixed an issue where the header layout was not updating after a font change.
  • Fixed issues related to the Tree Layout option becoming unresponsive.
Selected phylogenetic tree branch in MegAlign Pro

Protean 3D Enhancements and Updates

  • Added a new feature that colors your structure, or a selected region of your structure, according to an analysis method track, such as Charge Density or Hydropathy.
  • Added the ability to export analysis data, such as protein composition and details about each analysis method track applied to your protein sequence.
  • Updated the Biophysical Report to include several additional values, including sequence length, and the concentration of a protein.
Protein structure and analysis tracks in Protean 3D

SeqMan Ultra updates include fixes for the following issues:

  • An error when deleting a sequence range.
  • The Quick Details row being partially obscured in the Variant Table.
  • Difficulty pasting a sequence range copied from the Strategy View.
  • Difficulty pasting a sequence range copied from the Consensus into a text editor.
  • A column was being removed from the Variant Table after filtering.
  • Features in Feature Table were being listed with gapped (vs. ungapped) coordinates.
  • Sequence styles were being lost when exporting an image.
  • Inconsistencies with delete key edits.
  • Occasional crashes related to opening a BAM assembly on some macOS systems, and when starting a new Sanger project.
  • Unresponsiveness when attempting to export a zoomed out Alignment View.
  • Scrolling issues with Feature and Sequence tracks in Alignment View.
  • The reference ruler was starting at 0 instead of 1.
  • BAM .assemblies were not opening from Recent Documents list.

SeqBuilder Pro updates include fixes for the following issues:

  • Features being lost from clone “reference” in clone verification workflow.
  • A crash related to a specific set of steps in the Multisite Gateway cloning workflow.
  • The inability to reorder cloning fragments on macOS.
  • Window footer text sometimes appearing outside of the window.
  • Some single letter codes were not being recognized in the amino acid search.
  • Batch operations (run by SeqNinja) were not running on SeqBuilder-only licenses.
  • The inability to paste into the Sequence view from other applications on macOS Catalina or Big Sur.

If you are a current customer, upgrades are always included as part of your service plan. If your service plan has expired, please request a quote to renew!

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